SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NITROGEN HETEROCYCLES INCORPORATION INTO COUMARIN

Document Type : Original Article

Author

Chemistry Department, Faculty of Science, Girls Branch, Al-Azhar University, Nasr City, Cairo, Egypt.

Abstract

3-Carbethoxycoumarin derivatives were reacted with some neucleophilic reagents such as amines, hydrazines, urea derivatives and amino acids in order to study their effect on coumarin nucleus especially carbonyl coumarin and synthesis of new derivatives which have biological effects on microorganisms such as bacteria and fungi. The structural assignments of the new compounds were based on analytical and spectral data.

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