HETEROAROMATIZATION WITH SULFONAMIDO PHENYL ETHANONE: PART (IV). SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW N-ETHYL-N-METHYLBENZENESULFONAMIDE, 1,3,4-THIADIAZOLE, 1,3,4-THIADIAZINE, 4-OXOTHIAZOLIDINE AND PYRAZOLO[5,1-c][1,2,4]TRIAZINE DERIVATIVES

Document Type : Original Article

Authors

1 Chemistry Department, Faculty of Science, Al -Azhar University, Cairo, Egypt.

2 Organic Chemistry Department, Faculty of pharmacy (Boy's), Al-Azhar University, Nasr City, Cairo, Egypt

Abstract

This article describes the synthesis of some novel sulfonamide having the biologically active, hydrazones 7-11,1,3,4-thiadiazoles 15-18, 20,1,3,4-thiadiazine 19, 4-oxothiazolidines 21, 26-29 andpyrazolo[5,1-c][1,2,4]triazine 32 moieties starting with 4-acetyl-N-ethyl-N-methylbenzenesulfonamide (1). The structure of the newly synthesized compounds was confirmed by elemental analysis, IR, 1H NMR, and mass spectral data.

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