SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME 3-(AMINO OR ARYLIDINE)-2-PYRIDINYL-4(3H)-QUINAZOLINONE AND SOME OF THEIR COPPER COMPLEXES

Document Type : Original Article

Authors

1 Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo, Egypt

2 National Research Centre, Dokki, Cairo, Egypt

Abstract

Several 4(3H)-quinazolinones containing pyridine moiety were synthesized starting from substituted anthranilic acid derivatives. Copper complexes of 3-amino-2-pyridinyl-4(3H)-quinazolinones and some of their derivatives were synthesized and characterized. The synthesized compounds were screened for their anticonvulsant, analgesic, antitumor, as well as, their antimicrobial activities.

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