THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES

Document Type : Original Article

Authors

1 Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt

2 Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt

Abstract

The reaction of cyanoacetic acid hydrazide with 4-ethoxyphenylisothiocyanate gave the thiosemicarbazide derivative (3). The latter underwent a series of heterocyclization reactions when it reacts with either α-halo compounds, thioglycolic acid, acetylacetone, cinnamonitrile, or o-hydroxy aldehydes

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