THABET, H., HELAL, M., SALEM, M., FARRAG, A. (2011). THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES. Al-Azhar Bulletin of Science, 22(Issue 1-A), 85-96. doi: 10.21608/absb.2011.7179
H. KH. THABET; M. H. HELAL; M. A. SALEM; A. A. FARRAG. "THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES". Al-Azhar Bulletin of Science, 22, Issue 1-A, 2011, 85-96. doi: 10.21608/absb.2011.7179
THABET, H., HELAL, M., SALEM, M., FARRAG, A. (2011). 'THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES', Al-Azhar Bulletin of Science, 22(Issue 1-A), pp. 85-96. doi: 10.21608/absb.2011.7179
THABET, H., HELAL, M., SALEM, M., FARRAG, A. THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES. Al-Azhar Bulletin of Science, 2011; 22(Issue 1-A): 85-96. doi: 10.21608/absb.2011.7179
THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES
1Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt
2Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt
Abstract
The reaction of cyanoacetic acid hydrazide with 4-ethoxyphenylisothiocyanate gave the thiosemicarbazide derivative (3). The latter underwent a series of heterocyclization reactions when it reacts with either α-halo compounds, thioglycolic acid, acetylacetone, cinnamonitrile, or o-hydroxy aldehydes
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