EFFECT OF γ-RADIATION AND CHARACTERIZATION OF SYNTHESIZED BENZYLIDINE PHENYLTHIAZOLE AMINES AND SOME METAL-COMPLEX DERIVATIVES

ALY, R. O.; FARAG, R. S.; HASSAN, M. M.

doi:10.21608/absb.2011.7171

EFFECT OF γ-RADIATION AND CHARACTERIZATION OF SYNTHESIZED BENZYLIDINE PHENYLTHIAZOLE AMINES AND SOME METAL-COMPLEX DERIVATIVES

Document Type : Original Article

Authors

¹ National Center for Radiation Research and Technology, Nasr City, Cairo, Egypt

² Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt

10.21608/absb.2011.7171

Abstract

The Schiff-bases, I, II, III were prepared essentially by the condensation reaction between an amine, namely 2-amino-4-phenylthiazole, and an aldehyde: benzaldehyde (I), p-chlorobenzaldehyde (II) and p-nitrobenzaldehyde (III) in 1:1 molar ratio. The metal-complexes of Fe³⁺, Co²⁺, Ni²⁺, Cu²⁺, Zn²⁺ and La³⁺ were also synthesized. The structure elucidation was based on: elemental analysis, IR, UV-Visible, ¹H NMR and MS spectral analyses.
The impact of γ-radiation on the synthesized compounds was discussed via the post-radiation UV-Visible aftermaths. Some radiolysis products were postulated with the assistance of the obtained MS results. The thermal properties of the metal chelates were confirmed by the means of TGA results. The molar conductance of the derivatives supported the 1:1 and 1:2 electrolyte behaviors.
Metal-complex magnetic behavior in association with the UV-Visible data suggested the octahedral for all complexes except III_b is tetrahedral arrangement, whereas, Cu-complexes demonstrated distorted geometry. Furthermore, the Cu-complex of the ligand III_d proved to be very highly active against the Gram-positive Bacillus subtilis (NCTC-1040), whereas Co-complex of II_b showed significant inhibition, similarlyon Streptococcus pyogense (ATCC-19615) and on the fungus Aspergillus fungatus.

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