@article { author = {Gafar, Ahmed and Khalifa, Mahmoud and Elshaer, Fathy}, title = {PROTECTIVE AND THERAPEUTIC EFFECTS OF OLIVE OIL AND FICUSCARICA ON THEHISTOLOGICAL ANDCYTOLOGICAL INJURIESOF LIVER AND KIDNEY IN -IRRADIATED MALE ALBINO RATS}, journal = {Al-Azhar Bulletin of Science}, volume = {29}, number = {Issue 2-C}, pages = {69-88}, year = {2018}, publisher = {Al-Azhar University, Faculty of Science (Boys)}, issn = {1110-2535}, eissn = {2636-3305}, doi = {10.21608/absb.2018.33820}, abstract = {The present study was designed to determine the possible protective and therapeutic effects of olive oil and/or Ficus carica against radiation-induced cytological and histological changes in liver and Kidney of male albino rats. Irradiation was performed by whole-body exposure of rats to an acute single dose gamma radiation of 6 Gy. Irradiated rats received, via gavage, extra virgin olive oil (7.6 ml/kg b.wt), and/or extract of Ficus carica fruit (1 g/kg b.wt) before and/or after radiation exposure. Six rats were sacrificed on the 1st and 15th-day post-irradiation exposure at the control and treated irradiated subgroups. Time duration for this experiment was one month.The γ-Irradiation treated group revealedhisto pathological alterations in the hepatic and renal tissues on the 1st and 15th-day post-irradiation as compared to the control rats. The administration of the olive oil and/or Ficus carica showed beneficial results against the deleterious effects of γ-irradiation. A better ameliorative effect was noticed with the combined treatments that revealed the synergistic effect between them.In conclusion, the administration of the olive oil and/or Ficus carica provides considerable radioprotective and radiotherapeutic effects against whole body γ-radiation in male Wistar albino rats.}, keywords = {olive oil,Ficus carica,γ-radiation,histology,cytology}, url = {https://absb.journals.ekb.eg/article_33820.html}, eprint = {https://absb.journals.ekb.eg/article_33820_62b029273175a18dd49e7ca1ebe7994d.pdf} }